Strain SummaryC.129S2-Trp53^tm1Tyj

Strain Name	C.129S2-Trp53^tm1Tyj
Strain Type(s)	congenic • targeted mutation (knockout)
Strain Synonym(s)	Trp53^-/- • Trp53^-/- BALB/c
Description	Homozygous mice. The mutation had been backcrossed onto a BALB/cJ genetic background. The mutation was generated in a 129S2/SvPas genetic background.
Strain Genetics	List all models in MMHCdb carrying the Trp53^tm1Tyj allele Trp53^tm1Tyj / Trp53^tm1Tyj

Models
6 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Blood vessel hemangiosarcoma	Blood vessel		moderate	moderate			References: Cellurale C, PLoS One 2010;5(8):
Leukocyte lymphoma	Leukocyte		high	high			References: Cellurale C, PLoS One 2010;5(8):
Mammary gland carcinoma	Mammary gland		0	0			References: Cellurale C, PLoS One 2010;5(8):
Mesodermal cell/mesoblast sarcoma	Mesodermal cell/mesoblast		moderate	moderate			References: Cellurale C, PLoS One 2010;5(8):
(Unspecified organ) carcinoma	(Unspecified organ)		0	0			References: Cellurale C, PLoS One 2010;5(8):
(Unspecified organ) tumor	(Unspecified organ)				100		References: Cellurale C, PLoS One 2010;5(8):

Models