Strain SummaryC57BL/6-Tg(RIP1-Tag)2Dh Trp53^tm1Tyj

Strain Name	C57BL/6-Tg(RIP1-Tag)2Dh Trp53^tm1Tyj
Strain Type(s)	targeted mutation (knockout) • transgenic
Strain Synonym(s)	RIP-Tag2; p53^-/-; Arf^+/+ • p53-/- Arf+/+
Description	Compound mutant mice. These mice were generated by crossing strains that had previously been fully backcrossed onto C57BL/6. The genetic background may also include some DBA/2J and/or some 129X1/SvJ and/or some 129S2/SvPas.
Strain Genetics	Cdkn2a⁺ / Cdkn2a⁺
	List all models in MMHCdb carrying the Trp53^tm1Tyj allele Trp53^tm1Tyj / Trp53^tm1Tyj
	List all models in MMHCdb carrying the Tg(RIP1-Tag)2Dh allele Tg(RIP1-Tag)2Dh

Models
2 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Pancreas - Islet of Langerhans lesion - angiogenic	Pancreas - Islet of Langerhans					very high	References: Ulanet DB, PLoS One 2010;5(8):e12454
Pancreas - Islet of Langerhans tumor	Pancreas - Islet of Langerhans					observed - very high	References: Ulanet DB, PLoS One 2010;5(8):e12454

Models