Strain SummaryC57BL/6J-ApcMin/+ Tfamtm1.1Lrsn/+
Strain Name |
C57BL/6J-ApcMin/+ Tfamtm1.1Lrsn/+ |
Strain Type(s) |
chemically induced mutation • targeted mutation (conditional) • targeted mutation (knockout) |
Strain Synonym(s) |
APCMin/+ Tfam+/- |
Description |
Double hterozygous mice on a C57BL/6J background. The ApcMin allele came from an inbred C57BL/6J background, and the Tfam allele from a (129X1/SvJ x 129S1/Sv)F1-Kitl+ background backcrossed 10 times to C57BL/6J. |
Strain Genetics |
ApcMin / Apc+ |
| Tfamtm1.1Lrsn / Tfam+ |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon |
100 |
References: Woo DK, Am J Pathol 2012 Jan;180(1):24-31 |
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| Intestine - Small Intestine adenoma | Intestine - Small Intestine |
100 |
References: Woo DK, Am J Pathol 2012 Jan;180(1):24-31 |
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