Strain SummaryC57BL/6J-Espl1^Gt(XL058)Byg/+ Trp53^tm1Tyj

Strain Name	C57BL/6J-Espl1^Gt(XL058)Byg/+ Trp53^tm1Tyj
Strain Type(s)	gene trapped • targeted mutation (knockout)
Strain Synonym(s)	ESPL1^+/hypp53^-/-
Description	Heterozygous Espl1^Gt(XL058)Byg, homozygous Trp53^tm1Tyj mice on a C57BL/6J genetic background with possible contributions from 129P2/OlaHsd and 129S2/SvPas.
Strain Genetics	List all models in MMHCdb carrying the Trp53^tm1Tyj allele Trp53^tm1Tyj / Trp53^tm1Tyj
	List all models in MMHCdb carrying the Espl1^Gt(XL058)Byg allele Espl1^Gt(XL058)Byg / Espl1⁺

Models
12 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Leukocyte - Lymphocyte leukemia	Blood					observed	References: Mukherjee M, PLoS One 2011;6(7):e22167
Leukocyte - Lymphocyte lymphoma - mixed	Leukocyte - Lymphocyte					86 - 100	References: Mukherjee M, PLoS One 2011;6(7):e22167 Sites of Metastasis: Liver , Lung
Leukocyte - Lymphocyte lymphoma - mixed	Thymus					observed - 100	References: Mukherjee M, PLoS One 2011;6(7):e22167
Leukocyte - Lymphocyte lymphoma - mixed	Bone marrow					observed	References: Mukherjee M, PLoS One 2011;6(7):e22167
Leukocyte - Lymphocyte lymphoma - mixed	Spleen					observed	References: Mukherjee M, PLoS One 2011;6(7):e22167
Leukocyte - Lymphocyte lymphoma - mixed	Liver					observed	References: Mukherjee M, PLoS One 2011;6(7):e22167
Leukocyte - Lymphocyte lymphoma - mixed	Lung					observed	References: Mukherjee M, PLoS One 2011;6(7):e22167
Leukocyte - Lymphocyte lymphoma - mixed	Kidney					0	References: Mukherjee M, PLoS One 2011;6(7):e22167
Leukocyte - Lymphocyte lymphoma - mixed	Intestine - Large Intestine - Colon					observed	References: Mukherjee M, PLoS One 2011;6(7):e22167
Mesodermal cell/mesoblast sarcoma	Mesodermal cell/mesoblast					0	References: Mukherjee M, PLoS One 2011;6(7):e22167
(Unspecified organ) carcinoma	(Unspecified organ)					9	References: Mukherjee M, PLoS One 2011;6(7):e22167
(Unspecified organ) tumor	(Unspecified organ)					100	References: Mukherjee M, PLoS One 2011;6(7):e22167

Models