Strain Summary[not specified]-Plcb3tm1Dwu

Strain Name

 [not specified]-Plcb3tm1Dwu

Strain Type(s)

 targeted mutation (knockout)

Strain Synonym(s)

 PLC-β3-/-  •  PLC-β3-/-

Description

 Homozygous mice. The genetic background of these mice was not specified.

Strain Genetics

 Plcb3tm1Dwu / Plcb3tm1Dwu

Models

11 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Abdominal cavity hamartoma Abdominal cavity

0.8

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71

Abdominal cavity tumor Abdominal cavity

0.8

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte

observed

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71

Leukocyte - Myelocyte (Granulocyte) hyperplasia Spleen

89

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71

Leukocyte lymphoma Leukocyte

12.5

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71

Leukocyte lymphoma Thymus

10.2

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71

Sites of Metastasis: Bone marrow , Pleural cavity , Spleen , Thorax
Leukocyte lymphoma Lymph node

2.3

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71

Sites of Metastasis: Bone marrow , Spleen
Lung carcinoma Lung

1.6

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71

Ovary - Germ cell teratoma Ovary - Germ cell

0.8

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71

Skin carcinoma Neck

0.8

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71

Sites of Metastasis: Lymph node
(Unspecified organ) tumor (Unspecified organ)

17

References: Xiao W, Cancer Cell 2009 Aug 4;16(2):161-71