Strain Summary129-Brca2tm1Mbn/+

Strain Name

 129-Brca2tm1Mbn/+

Strain Type(s)

 targeted mutation (knockout)

Strain Synonym(s)

 129B2+/-

Description

 Heterozygous mice. The genetic background of these mice was a mixture of 129 substrains. Approximately 6-12% of this was 129P2/OlaHsd and the remainder was "129/SvEv" (substrain not specified).

Strain Genetics

 Brca2tm1Mbn / Brca2+

Models

15 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mammary gland tumor Mammary gland

0

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Mammary gland tumor Mammary gland diethylstilbestrol (DES)

0

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Ovary - Follicle cyst Ovary - Follicle diethylstilbestrol (DES)

20

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium diethylstilbestrol (DES)

29

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Uterus adenocarcinoma Uterus diethylstilbestrol (DES)

0

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Uterus carcinoma Uterus diethylstilbestrol (DES)

7.1

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Uterus dysplasia Uterus diethylstilbestrol (DES)

36

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Uterus hyperplasia Uterus diethylstilbestrol (DES)

36

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Uterus lesion Uterus diethylstilbestrol (DES)

43

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Uterus metaplasia Uterus diethylstilbestrol (DES)

7.1

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Uterus metaplasia - squamous Uterus diethylstilbestrol (DES)

14

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Uterus squamous cell carcinoma Uterus diethylstilbestrol (DES)

7.1

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

Vagina hyperplasia Vagina diethylstilbestrol (DES)

29

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

(Unspecified organ) hyperplasia - squamous (Unspecified organ) diethylstilbestrol (DES)

14

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9

(Unspecified organ) squamous cell carcinoma (Unspecified organ) diethylstilbestrol (DES)

0

References: Bennett LM, Cancer Res 2000 Jul 1;60(13):3461-9