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Strain SummaryB6.129S1-Pten^tm1Ppp/+

Strain Name	B6.129S1-Pten^tm1Ppp/+
Strain Type(s)	congenic • targeted mutation (knockout)
Strain Synonym(s)	het • Pten^+/-
Description	Heterozygous mice. The genetic background of these mice was congenic C57BL/6. The ES cells used to generate the mutation were derived from 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺ mice.
Strain Genetics	List all models in MMHCdb carrying the Pten^tm1Ppp allele Pten^tm1Ppp / Pten⁺

Models
17 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Adrenal gland - Medulla pheochromocytoma	Adrenal gland - Medulla		73.3	73.3			References: Papa A, Cell 2014 Apr 24;157(3):595-610
CNS - Brain - Cerebellum hamartoma	CNS - Brain - Cerebellum				0		References: Papa A, Cell 2014 Apr 24;157(3):595-610
Gallbladder papilloma	Gallbladder		46.7	50			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Intestine polyp	Intestine		66.7	83.3			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Leukocyte - Lymphocyte hyperplasia	Leukocyte - Lymphocyte					40	References: Papa A, Cell 2014 Apr 24;157(3):595-610
Leukocyte - Lymphocyte hyperplasia	Lymph node		93.3	93.3			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Liver adenoma	Liver		0				References: Papa A, Cell 2014 Apr 24;157(3):595-610
Mammary gland adenocarcinoma	Mammary gland		15.6 - 24.1				References: Papa A, Cell 2014 Apr 24;157(3):595-610
Mammary gland hyperplasia	Mammary gland		28.9				References: Papa A, Cell 2014 Apr 24;157(3):595-610
Mammary gland lesion	Mammary gland		69.0				References: Papa A, Cell 2014 Apr 24;157(3):595-610
Pituitary gland adenoma	Pituitary gland				68		References: Papa A, Cell 2014 Apr 24;157(3):595-610
Prostate gland adenocarcinoma	Prostate gland			13.3			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Prostate gland prostatic intraepithelial neoplasia (PIN)	Prostate gland			63.3			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Thyroid gland adenoma	Thyroid gland		9.5	13.3			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Thyroid gland cyst	Thyroid gland		61.9	50			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Uterus adenoma	Uterus		51.1				References: Papa A, Cell 2014 Apr 24;157(3):595-610
Uterus cyst	Uterus		31.1				References: Papa A, Cell 2014 Apr 24;157(3):595-610