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Strain SummaryB6.Cg-Pten^tm3.1Ppp/+

Strain Name	B6.Cg-Pten^tm3.1Ppp/+
Strain Type(s)	congenic • targeted mutation (knock-in)
Strain Synonym(s)	cs/+ • Pten^C124S/+ • Pten^C124S/+
Description	Heterozygous mice. The genetic background of these mice was congenic C57BL/6. The ES cells used to generate the mutation were derived from (C57BL/6 x 129S4/SvJae)F1 mice.
Strain Genetics	List all models in MMHCdb carrying the Pten^tm3.1Ppp allele Pten^tm3.1Ppp / Pten⁺

Models
18 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Adrenal gland - Medulla pheochromocytoma	Adrenal gland - Medulla		85	79.3			References: Papa A, Cell 2014 Apr 24;157(3):595-610
CNS - Brain - Cerebellum hamartoma	CNS - Brain - Cerebellum				25.9		References: Papa A, Cell 2014 Apr 24;157(3):595-610
Gallbladder papilloma	Gallbladder		60	82.8			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Intestine polyp	Intestine		80	82.8			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Leukocyte - Lymphocyte hyperplasia	Leukocyte - Lymphocyte					85.7	References: Papa A, Cell 2014 Apr 24;157(3):595-610
Leukocyte - Lymphocyte hyperplasia	Lymph node		97.5	100			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Liver adenoma	Liver		5.0				References: Papa A, Cell 2014 Apr 24;157(3):595-610
Lung adenoma	Lung		observed	observed			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Mammary gland adenocarcinoma	Mammary gland		22.5 - 33.3				References: Papa A, Cell 2014 Apr 24;157(3):595-610
Mammary gland hyperplasia	Mammary gland		22.5				References: Papa A, Cell 2014 Apr 24;157(3):595-610
Mammary gland lesion	Mammary gland		66.7				References: Papa A, Cell 2014 Apr 24;157(3):595-610
Pituitary gland adenoma	Pituitary gland				55.6		References: Papa A, Cell 2014 Apr 24;157(3):595-610
Prostate gland adenocarcinoma	Prostate gland			24.1			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Prostate gland prostatic intraepithelial neoplasia (PIN)	Prostate gland			62.1			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Thyroid gland adenoma	Thyroid gland		20	6.9 - 39.3			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Thyroid gland cyst	Thyroid gland		55	39.3			References: Papa A, Cell 2014 Apr 24;157(3):595-610
Uterus adenoma	Uterus		57.5				References: Papa A, Cell 2014 Apr 24;157(3):595-610
Uterus cyst	Uterus		22.5				References: Papa A, Cell 2014 Apr 24;157(3):595-610