Strain Summary[not specified]-Apc^tm2.1Cip/+ Lrig1^{tm1.1(cre/ERT2)Rjc}/+

Strain Name	[not specified]-Apc^tm2.1Cip/+ Lrig1^{tm1.1(cre/ERT2)Rjc}/+
Strain Type(s)	targeted mutation (conditional) • targeted mutation (knock-in)
Strain Synonym(s)	Lrig1-CreERT2/+;Apcfl/+
Description	Heterozygous Lrig1^{tm1.1(cre/ERT2)Rjc}, Apc^tm2.1Cip mice on an unspecified genetic background with possible contribution from 129S6/SvEvTac and 129P2/OlaHsd-Hprt^b-m3.
Strain Genetics	List all models in MMHCdb carrying the Lrig1^{tm1.1(cre/ERT2)Rjc} allele Lrig1^{tm1.1(cre/ERT2)Rjc} / Lrig1⁺
	List all models in MMHCdb carrying the Apc^tm2.1Cip allele Apc^tm2.1Cip / Apc⁺

Models
26 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Eye - Retina lesion - epithelial	Eye - Retina	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Gastrointestinal tract tumor	Gastrointestinal tract	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Large Intestine - Colon - Distal tumor	Intestine - Large Intestine - Colon - Distal	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Large Intestine - Colon - Distal tumor - luminal	Intestine - Large Intestine - Colon - Distal	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Large Intestine - Colon - Proximal tumor	Intestine - Large Intestine - Colon - Proximal	tamoxifen (for inducing expression from mutant alleles)				0	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Large Intestine - Colon adenoma - microadenoma	Intestine - Large Intestine - Colon	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Large Intestine - Colon lesion	Intestine - Large Intestine - Colon	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Small Intestine - Duodenum - Periampullary region adenoma	Intestine - Small Intestine - Duodenum - Periampullary region	tamoxifen (for inducing expression from mutant alleles)				80	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Small Intestine - Duodenum - Periampullary region tumor	Intestine - Small Intestine - Duodenum - Periampullary region	tamoxifen (for inducing expression from mutant alleles)				80	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Small Intestine - Duodenum tumor	Intestine - Small Intestine - Duodenum	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Small Intestine - Ileum tumor	Intestine - Small Intestine - Ileum	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Small Intestine - Jejunum tumor	Intestine - Small Intestine - Jejunum	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Small Intestine lesion	Intestine - Small Intestine	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine - Small Intestine tumor	Intestine - Small Intestine	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine dysplasia	Intestine	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine lesion	Intestine	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Intestine neoplasia	Intestine	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Stomach - Fundus dysplasia	Stomach - Fundus	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Stomach - Fundus hyperplasia - foveolar	Stomach - Fundus	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Stomach - Fundus lesion - dysplastic	Stomach - Fundus	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Stomach - Glandular - Pyloric antrum dysplasia - high grade	Stomach - Glandular - Pyloric antrum	tamoxifen (for inducing expression from mutant alleles)				observed - 100	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Stomach - Glandular - Pyloric antrum hyperplasia	Stomach - Glandular - Pyloric antrum	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Stomach - Glandular - Pyloric antrum lesion - dysplastic	Stomach - Glandular - Pyloric antrum	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Stomach - Glandular - Pylorus dysplasia - high grade	Stomach - Glandular - Pylorus	tamoxifen (for inducing expression from mutant alleles)				100	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23
Stomach - Glandular - Pylorus lesion - dysplastic	Stomach - Glandular - Pylorus	tamoxifen (for inducing expression from mutant alleles)				observed	References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Strain Name

Strain Type(s)

Strain Synonym(s)

Description

Strain Genetics

Models