Strain SummaryFVB/N-E2f3^tm1Lees/+ Tg(MMTV-PyVT)634Mul

Strain Name	FVB/N-E2f3^tm1Lees/+ Tg(MMTV-PyVT)634Mul
Strain Type(s)	targeted mutation (knockout) • transgenic
Strain Synonym(s)	E2F3^+/- • MMTV-PyMT634 E2F3^+/- • MMTV-PyMT E2F3^+/- • PyMT E2F3^+/-
Description	Compound mutant mice. The genetic background of these mice was reported to be "FVB". This cohort of mice was generated by interbreeding transgenic and knockout mice.
Strain Genetics	List all models in MMHCdb carrying the Tg(MMTV-PyVT)634Mul allele Tg(MMTV-PyVT)634Mul
	List all models in MMHCdb carrying the E2f3^tm1Lees allele E2f3^tm1Lees / E2f3⁺

Models
8 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Mammary gland tumor	Mammary gland					50 - 100	References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43 Sites of Metastasis: Lung
Mammary gland tumor - adenosquamous	Mammary gland					observed	References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43
Mammary gland tumor - glandular	Mammary gland					observed	References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43
Mammary gland tumor - microacinar	Mammary gland					observed	References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43
Mammary gland tumor - microacinar/adenosquamous	Mammary gland					observed	References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43
Mammary gland tumor - mixed	Mammary gland					observed	References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43
Mammary gland tumor - papillary	Mammary gland					observed	References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43
Mammary gland tumor - solid	Mammary gland					observed	References: Hollern DP, Mol Cell Biol 2014 Sep;34(17):3229-43

Models