Strain Summary[not specified]-Rb1^tm2Brn Tg(MMTV-cre)#Tfln

Strain Name	[not specified]-Rb1^tm2Brn Tg(MMTV-cre)#Tfln
Strain Type(s)	targeted mutation (conditional) • transgenic
Strain Synonym(s)	Rb^Δfl • Rb^?/? • Mixed_Rb • MMTV-Cre:Rb^fl/fl • MMTV-Cre:Rb^fl/fl;p107^+/+ • MMTV-Cre^NLST:Rb^fl/fl • RbΔf
Description	Compound mutant mice. The genetic background was described as a "mixed genetic background" but the contributing strains were not identified. It included at least some "129" (substrain not specified) and possibly some 129S2/SvPas.
Strain Genetics	List all models in MMHCdb carrying the Tg(MMTV-cre)#Tfln allele Tg(MMTV-cre)#Tfln
	List all models in MMHCdb carrying the Rb1^tm2Brn allele Rb1^tm2Brn / Rb1^tm2Brn
	Rbl1⁺ / Rbl1⁺

Models
4 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Mammary gland adenocarcinoma - squamous	Mammary gland		observed				References: Jiang Z, J Clin Invest 2010 Sep 1;120(9):3296-309
Mammary gland carcinoma	Mammary gland					observed	References: Pfefferle AD, Genome Biol 2013;14(11):R125
Mammary gland hyperplasia	Mammary gland		observed				References: Jiang Z, J Clin Invest 2010 Sep 1;120(9):3296-309
Mammary gland tumor	Mammary gland		100				References: Jiang Z, J Clin Invest 2010 Sep 1;120(9):3296-309

Models