Strain Summary[not specified]-Rb1tm2Brn Rbl1tm1Tyj/+ Tg(MMTV-cre)4Mam

Strain Name

[not specified]-Rb1tm2Brn Rbl1tm1Tyj/+ Tg(MMTV-cre)4Mam

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

MMTV-CreD:Rbfl/fl;p107+/-

Description

Compound mutant mice. The genetic background was described as a "mixed genetic background" but the contributing strains were not identified. It included at least some "129" (substrain not specified), 129S2/SvPas, FVB, and C57BL/6.

Strain Genetics

Tg(MMTV-cre)4Mam
Rb1tm2Brn / Rb1tm2Brn
Rbl1tm1Tyj / Rbl1+

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mammary gland tumor Mammary gland

observed

References: Jiang Z, J Clin Invest 2010 Sep 1;120(9):3296-309