Strain SummaryC.129(B6)-Cdkn2ctm1Yxi

Strain Name

C.129(B6)-Cdkn2ctm1Yxi

Strain Type(s)

congenic  •  targeted mutation (knockout)

Strain Synonym(s)

Balb/c-p18  •  BALBc_p18null  •  p18  •  p18-/-  •  p18?/?  •  p18null  •  p18Ink4c-null

Description

Homozygous mice. These mice were congenic on BALB/c and were derived from mice generated in 129/Sv ES cells and previously maintained on a C57BL/6 background.

Strain Genetics

Cdkn2ctm1Yxi / Cdkn2ctm1Yxi

Models

13 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Lung tumor Lung

observed

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

Mammary gland carcinoma Mammary gland

observed

References: Pfefferle AD, Genome Biol 2013;14(11):R125

Mammary gland carcinoma - ductal Mammary gland

6.7

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

Sites of Metastasis: Lung

Mammary gland carcinoma in situ - ductal Mammary gland

observed

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

Mammary gland hyperplasia Mammary gland

observed

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

Mammary gland lesion Mammary gland

0

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

Mammary gland tumor Mammary gland

23

60 - 88

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

Mammary gland tumor - luminal Mammary gland

observed

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

Pancreas tumor Pancreas

observed

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

Pituitary gland tumor Pituitary gland

observed

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

Testis tumor Testis

observed

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

Thyroid gland tumor Thyroid gland

observed

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401

(Unspecified organ) tumor (Unspecified organ)

observed

References: Pei XH, Cancer Cell 2009 May 5;15(5):389-401