Strain SummaryB6.129-Kras^tm4.1Bbd

Strain Name	B6.129-Kras^tm4.1Bbd
Strain Type(s)	congenic • targeted mutation (knock-in)
Strain Synonym(s)	B6-KRas^V14I • C57BL/6J.OlaHsd-KRas^V14I
Description	Homozygous mice. These mice had been backcrossed onto C57BL/6JOlaHsd. The genetic background also contained 129 (including at least 129X1/SvJ and/or 129S1/Sv).
Strain Genetics	List all models in MMHCdb carrying the Kras^tm4.1Bbd allele Kras^tm4.1Bbd / Kras^tm4.1Bbd

Models
1 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Leukocyte - Myelocyte (Granulocyte) hyperplasia	Spleen	PD0325901 (MEK inhibitor)				observed	References: Hernandez-Porras I, Rare Dis 2015;3(1):e1045169

Models