Strain SummaryCD-1;B6-Tg(MMTV-Myc)141-3Led Tg(MMTV-vHaras)SH1Led
Strain Name |
CD-1;B6-Tg(MMTV-Myc)141-3Led Tg(MMTV-vHaras)SH1Led |
Strain Type(s) |
transgenic |
Strain Synonym(s) |
B6;CD-1-TgN(MMTV-cmyc)141-3Led TgN(MMTV-vHaras)SH1Led • myc/ras • ras myc • MMTV/c-myc MMTV/v-Ha-ras • TG.M/SH • TG.MSH |
Description |
Generated by crossing 2 transgenic strains. Transgenic lines also referred to as "TG.M" (or "MMTV-H3 myc") and "TG.SH" respectively. The genetic background of these mice is a mixture of C57BL/6J and CD-1. |
Strain Genetics |
Tg(MMTV-vHaras)SH1Led |
| Tg(MMTV-Myc)141-3Led |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Eye - Harderian gland hyperplasia | Eye - Harderian gland |
observed |
observed |
observed |
References: Sinn E, Cell 1987 May 22;49(4):465-75 |
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| Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma | Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell |
9.5 |
References: Sinn E, Cell 1987 May 22;49(4):465-75 |
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| Leukocyte - Lymphocyte - B-lymphocyte lymphoma - immunoblastic | Leukocyte - Lymphocyte - B-lymphocyte |
observed |
observed |
29 |
References: Sinn E, Cell 1987 May 22;49(4):465-75 |
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| Mammary gland adenocarcinoma | Mammary gland |
high |
high |
86 |
References: Sinn E, Cell 1987 May 22;49(4):465-75 |
|||
| Mammary gland tumor | Mammary gland |
70 |
References: Cardiff RD, Am J Pathol 1991 Sep;139(3):495-501 |
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| Salivary gland - Parotid adenocarcinoma | Salivary gland - Parotid |
19 |
References: Sinn E, Cell 1987 May 22;49(4):465-75 |
|||||
| Salivary gland adenocarcinoma | Salivary gland |
observed |
observed |
References: Sinn E, Cell 1987 May 22;49(4):465-75 |
||||
| Seminal vesicle tumor | Seminal vesicle |
observed |
observed |
References: Sinn E, Cell 1987 May 22;49(4):465-75 |
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