Strain SummaryC57BL/6-Apc^tm1Mmt/+ Kras^tm4Tyj/+ Lgr5^{tm1(cre/ERT2)Cle}/+

Strain Name	C57BL/6-Apc^tm1Mmt/+ Kras^tm4Tyj/+ Lgr5^{tm1(cre/ERT2)Cle}/+
Strain Type(s)	targeted mutation (conditional) • targeted mutation (knockout)
Strain Synonym(s)	Kras^G12DLgr5^{tm1(Cre/ERT2)Cle}MinApc^?716/+ • KLM
Description	Heterozygous Apc, Kras, Lgr mice on a C57BL/6 background with contribution from 129P2/OlaHsd and 129S2/SvPas.
Strain Genetics	List all models in MMHCdb carrying the Apc^tm1Mmt allele Apc^tm1Mmt / Apc⁺
	List all models in MMHCdb carrying the Lgr5^{tm1(cre/ERT2)Cle} allele Lgr5^{tm1(cre/ERT2)Cle} / Lgr5⁺
	List all models in MMHCdb carrying the Kras^tm4Tyj allele Kras^tm4Tyj / Kras⁺

Models
3 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon - Distal tumor	Intestine - Large Intestine - Colon - Distal	Bacteroides fragilis			55.56 - 100		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon - Proximal tumor	Intestine - Large Intestine - Colon - Proximal	Bacteroides fragilis			11.11 - 33.33		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	Bacteroides fragilis			77.78		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():

Models