Strain SummaryC.129S2(B6)-Trp53tm1Tyj/J

Strain Name

 C.129S2(B6)-Trp53tm1Tyj/J

Strain Type(s)

 congenic  •  targeted mutation (knockout)

Strain Synonym(s)

 BALB/cJ-Trp53tm1Tyj  •  BALB/c p53+/-  •  BALB-p53+/?  •  C.129S2-Trp53tm1Tyj/J  •  p53&delta

Description

 Heterozygous mice. These mice have been fully backcrossed onto BALB/cJ. The original mutation was generated using 129S2/SvPas ES cells and was crossed to C57BL/6 before being backcrossed to BALB/cJ.

Strain Links

 • JAX Mice

Strain Genetics

 Trp53tm1Tyj / Trp53+

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Blood vessel hemangiosarcoma Blood vessel

0

9.1

1.3

References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38

Bone osteosarcoma Bone

3.0

9.1

3.8

References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38

Leukocyte lymphoma Leukocyte

12

27

14

20

References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38

Mammary gland carcinoma Mammary gland

64

0

55

References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38

(Unspecified organ) sarcoma (Unspecified organ)

6.0

9.1

6.4

References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38

(Unspecified organ) tumor (Unspecified organ)

21

45

100

References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38