Model DetailsLung hyperplasia - neuroendocrine

Model Name

Lung hyperplasia - neuroendocrine

Strain

NMRI-Foxn1nu

Tumor Inducing Agent(s)

Genetic Modification : Q Y4Linear-Cationic polymer Y4Linear carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

Tumor Synonyms

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH)  •  lung Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH)

Strain Synonyms

NMRI-Foxn1nu/Foxn1nu  •  NMRI-Foxn1nu/nu  •  NMRInude
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Lung Unspecified

0%

(0 of 8 mice)
20-36 months
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121
Lung Unspecified

0%

(0 of 9 mice)
20-36 months
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121