Model DetailsLung hyperplasia - neuroendocrine
Model Name |
Lung hyperplasia - neuroendocrine | Strain |
NMRI-Foxn1nu |
Tumor Inducing Agent(s) |
Genetic Modification : Q Y4L5-Cationic polymer Y4L5 carrying RNAP guides for Rb, Rb1l, Pten, and Trp53. |
Tumor Synonym |
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) |
Strain Synonyms |
NMRI-Foxn1nu/Foxn1nu • NMRI-Foxn1nu/nu • NMRInude |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Lung | Unspecified |
observed |
20-36 months |
|
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121 |
| Lung | Unspecified |
10% (1 of 9 mice) |
20-36 months |
|
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121 |