Model DetailsBone osteosarcoma(Bone - Jaw)

Model Name

 Bone osteosarcoma  (Bone - Jaw)

Strain
B6.129S7-Trp53tm1Brd/+

Tumor Inducing Agent(s)

 None (spontaneous)

Tumor Synonyms

 osteosarcoma of the skull  •  osteosarcoma  •  osteosarcoma of the maxilla or mandible

Strain Synonyms

 p53+/- Deficient  •  p53+/-  •  C57Bl/6Tac-[KO]Trp53N5-T  •  C57bl/6N12-Trp53 heterozygous (+/-)  •  p53-deficient  •  B6.129-Trp53tm1Brd/+  •  p53(+/-)  •  C57BL/6TacfBR-[KO] p53 N5 heterozygous mice  •  p53+/-  •  p53+/-  •  heterozygous p53 knockout
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Bone - Jaw Male

1.9%

(2 of 108 mice) 		~33 weeks
  • Notes

    Reproductive Status: reproductive status not specified

 Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11
Bone - Jaw Female

0%

(0 of 109 mice) 		~33 weeks
  • Notes

    Reproductive Status: reproductive status not specified

 Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11