Model DetailsUrinary bladder metaplasia - squamous
Model Name |
Urinary bladder metaplasia - squamous | Strain |
B6.129S7-Trp53tm1Brd/+ |
Tumor Inducing Agent(s) |
Chemical/Drug : p-cresidine |
Tumor Synonyms |
bladder lesion • squamous metaplasia |
Strain Synonyms |
p53+/- Deficient • p53+/- • C57Bl/6Tac-[KO]Trp53N5-T • C57bl/6N12-Trp53 heterozygous (+/-) • p53-deficient • B6.129-Trp53tm1Brd/+ • p53(+/-) • C57BL/6TacfBR-[KO] p53 N5 heterozygous mice • p53+/- • p53+/- • heterozygous p53 knockout |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Urinary bladder | Male |
53.3% (8 of 15 mice) |
32-36 weeks |
|
Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
| Urinary bladder | Female |
26.7% (4 of 15 mice) |
32-36 weeks |
|
Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |