Model DetailsLung carcinoma - large cell neuroendocrine
Model Name |
Lung carcinoma - large cell neuroendocrine | Strain |
B6.Cg-Gt(ROSA)26Sortm1.3(CAG-tdTomato,-EGFP)Pjen |
Tumor Inducing Agent(s) |
Genetic Modification : Qfrt Y4 Linear-Cationic polymer Y4 Linear carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt |
Tumor Synonyms |
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) • large cell neuroendocrine carcinoma (LCNEC) • lung large cell neuroendocrine carcinoma (LCNEC) • Large Cell Neuroendocrine Carcinoma (LCNEC) • small cell lung cancer (SCLC) |
Strain Synonym |
RC::FLTG |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Lung | Unspecified |
60% (9 of 15 mice) |
20-36 months |
|
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121 |
| Lung | Unspecified |
7% (1 of 15 mice) |
20-36 months |
|
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121 |
| Lung | Unspecified |
7% (1 of 15 mice) |
20-36 months |
|
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121 |
| Lung | Unspecified |
observed |
20-36 months |
|
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121 |
| Lung | Unspecified |
7% (1 of 15 mice) |
20-36 months |
|
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121 |