Model DetailsLung hyperplasia - neuroendocrine

Model Name

Lung hyperplasia - neuroendocrine

Strain

B6.Cg-Gt(ROSA)26Sortm1.3(CAG-tdTomato,-EGFP)Pjen

Tumor Inducing Agent(s)

Genetic Modification : Qfrt Y4 Linear-Cationic polymer Y4 Linear carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

Tumor Synonyms

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH)  •  Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH)

Strain Synonym

RC::FLTG
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Lung Unspecified

observed

20-36 months
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121
Lung Unspecified

7%

(1 of 15 mice)
20-36 months
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121