Model DetailsLeukocyte - Myelocyte (Granulocyte) hyperplasia(Spleen)

Model Name

Leukocyte - Myelocyte (Granulocyte) hyperplasia  (Spleen)

Strain

B6.129-Krastm4.1Bbd

Tumor Inducing Agent(s)

Chemical/Drug : PD0325901 (MEK inhibitor)

Tumor Synonyms

myeloproliferative disease (MPD)  •  splenomegaly

Strain Synonyms

C57BL/6J.OlaHsd-KRasV14I  •  B6-KRasV14I
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Spleen Unspecified

observed

6 months
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Hernandez-Porras I, Rare Dis 2015;3(1):e1045169